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Dr Larissa von Krbek


Larissa von Krbek received a Bachelor of Science in chemistry from the Freie Universität Berlin, Germany, in 2010, having completed a Bachelor thesis in the group of Prof. Dr. Hans-Ulrich Reißig on carbohydrate-mimetics synthesis. In 2012, she obtained her Master’s degree, working on multivalent supramolecular complexes under supervision of Prof. Dr. Christoph A. Schalley at the Freie Universität Berlin. She was awarded a fellowship of the German Academic Foundation (Studienstiftung des deutschen Volkes) to continue her work as a PhD student on the thermodynamic analysis of multivalent crown-ether/ammonium systems in the group of Prof. Dr. Christoph A. Schalley. During her PhD studies, Larissa enjoyed a pre-doctoral stay in the laboratories of Jonathan Nitschke, where she explored the subcomponent self-assembly of crown-ether capped metalorganic cages. In November 2016, she obtained a Dr. rer. nat. in chemistry.
She joined the group of Jonathan Nitschke as a postdoctoral research fellow in January 2017, where she is now working on stimuli responsive metal-organic cages and combining cages with classical supramolecular crown-ether/ammonium motives.

In April 2017, Larissa was awarded a postdoctoral affiliation at Christ's College Cambridge and in July 2017, a Feodor Lynen Research Fellowship of the Alexander von Humboldt Foundation.

Email:   lv305 ( e )



10. Strategies for binding multiple guests in molecular coordination cages

F. J. Rizzuto, L. K. S. von Krbek, J. R. Nitschke,

Nat. Rev. Chem. 2019, 3(4), 204–222.

9. Multivalent Crown-ether Receptors Enable Allosteric Regulation of Anion Exchange in an Fe₄L₆ Tetrahedron

Larissa K. S. von Krbek+, Derrick A. Roberts+, Ben S. Pilgrim, Christoph A. Schalley,

Jonathan R. Nitschke,

Angew. Chem. Int. Ed. 201857(43), 14121–14124.

8. Assessing cooperativity in supramolecular systems

Larissa K. S. von Krbek, Christoph A. Schalley, Pall Thordarson,

Chem. Soc. Rev. 2017, 46(9), 2622–2637.

7. The Delicate Balance of Preorganisation and Adaptability in Multiply Bonded Host–Guest Complexes

L. K. S. von Krbek, A. J. Achazi, S. Schoder, M. Gaedke, T. Biberger, B. Paulus, C. A. Schalley,

Chem.—Eur. J. 2017, 23(12), 2877–2883.

6. Allosteric and Chelate Cooperativity in Divalent Crown Ether–Ammonium Complexes with Strong Binding Enhancements

L. K. S. von Krbek, A. J. Achazi, M. Solleder, M. Weber, B. Paulus, C. A. Schalley,

Chem.—Eur. J. 2016, 22(43), 15475–15484.

5. Thermodynamic Analysis of Allosteric and Chelate Cooperativity in Di- and Trivalent Ammonium/Crown-Ether Pseudorotaxanes

K. Nowosinski, L. K. S. von Krbek, N. L. Traulsen, C. A. Schalley,

Org. Lett. 2015, 17(20), 5076–5079.

4. Theoretical and Experimental Investigation of Crown/Ammonium Complexes in Solution

A. J. Achazi, L. K. S. von Krbek, C. A. Schalley, B. Paulus,

J. Comput. Chem. 2016, 37(1), 18–24.

3. Preorganization is the Key: Synthesis of Discrete Di- and Tetravalent Porphyrin Pseudorotaxanes

M. Lohse, L. K. S. von Krbek, S. Radunz, S. Moorthy, C. A. Schalley, S. Hecht,

Beilstein J. Org. Chem. 2015, 11, 748–762.

2. Gating the photochromism of an azobenzene by strong host–guest interactions in a divalent pseudo[2]rotaxane

M. Lohse, K. Nowosinski, N. L. Traulsen, A. J. Achazi, L. K. S. von Krbek, B. Paulus, C. A. Schalley, S. Hecht,

Chem. Commun. 2015, 51(48), 9777–9780.

1.  Synthesis and Coordinative Layer-by-Layer Deposition of Pyridine-Functionalized Gold Nanoparticles and Tetralactam Macrocycles on Silicon Substrates

C. H.-H. Traulsen, V. Kunz, T. Heinrich, S. Richter, M. Holzweber, A. Schulz, L. K. S. von Krbek, U. T. J. Scheuschner, J. Poppenberg, W. E. S. Unger, C. A. Schalley,

Langmuir 2013, 29(46), 14284–14292.

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